so I'm kind of expressing my bioengineering side here well I think it's great to include the other organs and tissue systems of the body because as we both know that the narrow definition of just hypothalamic pituitary adrenal it can't be just that right no it can't no yeah it doesn't tell the whole story so if you look at the the main hormones in a a young woman who's in her teenage years the hypothalamic pituitary adrenal gonadal part of that is not fully mature so they're more likely to skip periods especially under stress they have a lot of influences it really doesn't get well established until you're done with adolescence and I'm told that adolescence now is still like age 25 to 26. I heard that and I was like I've got two daughters and I was like that's a really long time and not just a psychologically defined or bio psychosocial mostly psychologically defined